In a society where oppression and conformity rule the masses and the slightest unusual behavior could be seen as treasonous, Wynter Reeves would do just about anything to stay unnoticed. Yet when she succumbs to a rare and debilitating illness, she unwillingly attracts the attention of the State—in particular, the feared research facility known as the DSD.

Through them she learns of the true nature of her condition, a disease known only as Ultraxenopia.